| 0 | - | cover | 1 | pencils: Norman Mingo; inks: Norman Mingo; colors: Norman Mingo | Alfred E. Neuman |
| 1 | Let Us Spray | promo (ad from the publisher) | 1 | pencils: Al Jaffee; inks: Al Jaffee | |
| 2 | - | letters page | 0.5 | script: Jerry De Fuccio | |
| 3 | - | statement of ownership | 0.25 | script: William M. Gaines | |
| 4 | Will Success Spoil Charlie Brown? | comic story | 4 | script: Larry Siegel; pencils: Jack Rickard; inks: Jack Rickard | Charlie Brown; Lucy Van Pelt; Linus Van Pelt; Schroeder; Pig Pen; Violet; Snoopy; Patty; Shermy |
| 5 | Letters to a Congressman...That Were Answered by Form Letters by That Congressman | text story | 2 | script: Peter Andrews | |
| 6 | Out West | comic story | 2 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 7 | A Mad Look at Sky Diving | comic story | 5 | script: Dick DeBartolo; pencils: Jack Davis; inks: Jack Davis | |
| 8 | Drawn Out Dramas | cartoon | 0 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 9 | Mad Graffiti | comic story | 2 | script: Arnie Kogen; pencils: Bob Clarke; inks: Bob Clarke; letters: Bob Clarke | |
| 10 | Honest Comments on TV | comic story | 4 | script: Tom Koch; pencils: Jack Rickard; inks: Jack Rickard | Robert Kennedy; Pete Franklin; Richard Nixon; Lawrence Spivak; Lyndon Johnson |
| 11 | The Mad Library of Extremely Thin Books | illustration | 2 | script: Frank Jacobs | |
| 12 | Spy Vs. Spy | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy; The White Spy |
| 13 | Air Pollution Problems of the Future | comic story | 3 | script: Sy Reit; pencils: George Woodbridge; inks: George Woodbridge | |
| 14 | You Know You're Really Married When... | comic story | 2 | script: Phil Hahn, Jack Hanrahan; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 15 | The Lighter Side of Clothes | comic story | 4 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 16 | Welcome Aboard Speeches | comic story | 2 | script: Sy Reit; pencils: Joe Orlando; inks: Joe Orlando | |
| 17 | One Day Last Summer | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 18 | Mad's Medical Mother Goose | comic story | 3 | script: Larry Siegel; pencils: Al Jaffee; inks: Al Jaffee | |
| 19 | Spy Vs. Spy | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy; The White Spy |
| 20 | The "Sam Pebbles" | comic story | 5 | script: Stan Hart; pencils: Mort Drucker; inks: Mort Drucker | Steve McQueen [as Jake [Jack] Holenhead]; Candice Bergen [as Shrilly DuGood]; Edgar Bergen; Richard Crenna [as the Captain]; Richard Attenborough [as Frenchy]; Larry Gates [as the missionary]; Mako [as the coolie]; Emmanuelle Arsan [as Dingaling]; Popeye (cameo); Mao tse-Tung; Chou en-Lai |
| 21 | Mad's Modern Believe It or Nuts | cartoon | 1 | script: Arnie Kogen; pencils: Bob Clarke; inks: Bob Clarke; letters: Bob Clarke | Lyndon Johnson; Hubert Humphrey; Wilt Chamberlain |
| 22 | What Is the Most Expensive Accessory Item Young Car-Buyers Purchase? | illustration | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | |
| 23 | The Further She Is...The Closer You Should Look | photo story | 1 | pencils: Irving Schild; inks: Irving Schild; colors: Irving Schild | |