| 0 | Special Inflation Issue | cover | 1 | pencils: Norman Mingo; inks: Norman Mingo; colors: Norman Mingo | Alfred E. Neuman |
| 1 | A Fish Tale | cartoon | 1 | script: Al Jaffee; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 2 | Vital Features | table of contents | 1 | pencils: various; inks: various; letters: typeset | |
| 3 | Why Not Have the Next Issue Sent Directly to Your Home? | promo (ad from the publisher) | 0.28 | pencils: Paul Coker; inks: Paul Coker | |
| 4 | Moving Pictures? | promo (ad from the publisher) | 0.05 | pencils: Norman Mingo; inks: Norman Mingo | Alfred E. Neuman |
| 5 | Random Samplings of Reader Mail | letters page | 1 | script: Albert B. Feldstein; pencils: John C. Goodwin; inks: John C. Goodwin | Albert B. Feldstein; Herman Ahrens |
| 6 | Don Martin Comes On Strong | promo (ad from the publisher) | 0.67 | pencils: Don Martin; inks: Don Martin | |
| 7 | Five Easy Pages (and Two Hard Ones)! | comic story | 7 | script: Lou Silverstone; pencils: Mort Drucker; inks: Mort Drucker | Bing Crosby, Bob Hope, Liberace, Joe Namath, Schroeder |
| 8 | Very Early One Morning | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 9 | A Mad Look at Then...and Now (Or "We've Come a Long Way, Baby!") | photo story | 4 | script: Max Brandel; pencils: United Press International, World Wide Photos; inks: United Press International, World Wide Photos | Richard Nixon |
| 10 | The Lighter Side of Boating | comic story | 5 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | Roger Kaputnik |
| 11 | The Mad Orthodontia Primer | text article | 3 | script: Larry Siegel; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 12 | That Sinking Feeling... | text article | 2 | script: Max Brandel, Frank Jacobs, Richard M. Nixon; pencils: U.P.I.; inks: U.P.I. | Richard Nixon |
| 13 | - | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy, The White Spy |
| 14 | What Coaches Say... | text story | 3 | script: Paul Peter Porges; pencils: Jack Davis; inks: Jack Davis | |
| 15 | Greeting Cards for the Sexual Revolution | text story | 3 | script: Frank Jacobs; pencils: Bob Clarke; inks: Bob Clarke | |
| 16 | Hawks and Doves; Fowl Play Dept. | comic story | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | Major Hawks; Private Doves |
| 17 | A MAD Look at Palm Reading | comic story | 2 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | Alfred E. Neuman |
| 18 | - | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy, The White Spy |
| 19 | Excuses, Excuses! | comic story | 3 | script: Dick DeBartolo, Donald K. Epstein; pencils: George Woodbridge; inks: George Woodbridge | |
| 20 | "Prison" Record Albums of the Future | text story | 2 | script: Arnie Kogen; pencils: Jack Rickard; inks: Jack Rickard | Johnny Cash; Jim Nabors; Engelbert Humperdinck; Connie Francis; Wayne Newton; Kate Smith; The King Sisters |
| 21 | One Day in a Pet Shop | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 22 | The Foul and the Prissy Cats | comic story | 6 | script: Stan Hart; pencils: Angelo Torres; inks: Angelo Torres | Barbra Streisand [as Dooris] |
| 23 | Drawn-Out Drams | comic story | 0 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 24 | What New Phenomena Will Send Workingmen's Temperatures Soaring This Summer? | cartoon | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee; colors: Al Jaffee | |
| 25 | The Modern Crucifixtion | cartoon | 1 | script: Max Brandel; pencils: Irving Schild; inks: Irving Schild; colors: Irving Schild | |