| 0 | Mad Proudly Salutes American Industry | cover | 1 | pencils: Norman Mingo; inks: Norman Mingo | Alfred E. Neuman |
| 1 | One Day in the Jungle | comic story | 1 | script: Sergio Aragonés; pencils: George Woodbridge; inks: George Woodbridge; colors: George Woodbridge | |
| 2 | Why Not Have the Next Issue Sent Directly to Your Home? | promo (ad from the publisher) | 0.33 | pencils: Paul Coker; inks: Paul Coker | |
| 3 | - | letters page | 0.67 | script: Jerry De Fuccio; pencils: Don Martin; inks: Don Martin | |
| 4 | Mad Photoetry | photo story | 4 | script: Max Brandel | Golda Meir; Richard Nixon; Shirley Chisholm; Bella Abzug; Gloria Steinum; Pope Paul VI; Adam Clayton Powell; Spiro Agnew |
| 5 | In the Operating Room with Don Martin | comic story | 2 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 6 | Mad's Songbook for the '72 Candidates | comic story | 3 | script: Frank Jacobs; pencils: David Gantz; inks: David Gantz | Richard Nixon; George Wallace; Spiro Agnew; Edward Kennedy; George McGovern; Hubert Humphrey; Nelson Rockefeller; John Lindsey; Edmund Muskie; Alfred E. Neuman |
| 7 | Drawn Out Dramas | cartoon | 0 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 8 | Miracle Center | comic story | 5 | script: Dick DeBartolo; pencils: Angelo Torres; inks: Angelo Torres | Chad Everett [as Dr. Gammon]; James Daly [as Dr. Lockjaw]; Chris Hutson [as Nurse Chamberpot] |
| 9 | Letters from the Internal Revenue Service | text story | 2 | script: Dick DeBartolo, Donald K. Epstein | |
| 10 | A Mad Look at TV Sports Interviews - - Past, Present and Future | comic story | 5 | script: Tom Koch; pencils: Jack Davis; inks: Jack Davis | |
| 11 | The Small Businessman | comic story | 1 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 12 | The Lighter Side of Modern Technology | comic story | 5 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 13 | Back in the Operating Room with Don Martin During a Heart Transplant | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 14 | When Somebody Says... | comic story | 3 | script: Lou Silverstone; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 15 | Mad's Auto Manufacturer of the Year | comic story | 5 | script: Tom Koch, Earle Doud; pencils: George Woodbridge; inks: George Woodbridge | Walter Cronkite; Edsel Lemmon |
| 16 | You Know Your Days Are Numbered When... | comic story | 2 | script: Tom Koch; pencils: Bob Clarke; inks: Bob Clarke | |
| 17 | Carnival Knowledge | comic story | 7 | script: Larry Siegel; pencils: Mort Drucker; inks: Mort Drucker | Jack Nicholson [as Yawnathan]; Mortimer Snerd (cameo); Art Garfunkel [as Sappy]; Candice Bergen [as Schmoozin]; Ann-Margret [as Boobie]; Carol Kane [as Jennifer] |
| 18 | What Beloved American Animal Will Never Become Extinct Because of Overwhelming Public Support? | illustration | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee; colors: Al Jaffee | |
| 19 | Caged Dove | cartoon | 1 | script: Arnoldo Franchioni; pencils: Arnoldo Franchioni; inks: Arnoldo Franchioni | |