| 0 | Meet Our NEW Staff! | cover | 1 | pencils: Irving Schild, Jack Syracuse; inks: Irving Schild, Jack Syracuse; colors: Irving Schild, Jack Syracuse | Alfred E. Neuman |
| 2 | Departments | table of contents | 1 | script: John Ficarra; pencils: Tom Richmond; inks: Tom Richmond | Mr. Jingles |
| 3 | Meet The New Staff of MAD | comic story | 2 | script: Jeff Kruse; pencils: Tom Richmond; inks: Tom Richmond | King Kong |
| 4 | Random Samplings of Reader Mail | letters page | 2.67 | script: John Ficarra, Jamie Schaub; pencils: Jamie Schaub; inks: Jamie Schaub; colors: Jamie Schaub | Derek; Drew Morgan; Black Spy; White Spy; Helter Siqueira; Marcelo Siqueira; Evan Burke; Gallagher (comedian) |
| 7 | - | credits, title page | 0.33 | letters: typeset | |
| 8 | Own A Piece Of MAD History! | promo (ad from the publisher) | 1 | pencils: Kelly Freas; inks: Kelly Freas; colors: Kelly Freas | Alfred E. Neuman |
| 9 | The Monkey-Lini Pages | comic story | 3 | script: various; pencils: various; inks: various; letters: typeset | Chuckles; Jo-Jo; Joe Bittermonkey; Baboonsbury; Mr. Dookie |
| 10 | MONKey | comic story | 3 | script: Charlie Kadau; pencils: Mort Drucker; inks: Mort Drucker | Jason Gray-Stanford [as Dishwater]; Snoopy (cameo); Ted Levine [as Capt. Startlebuyer]; Mr. Paris; Adrian Monkey; Traylor Howard [as Nattily Teaser]; janitor; Stanley Kamel [as Monkey's psychologist] |
| 11 | A MAD Look at Humans | comic story | 3 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 12 | MOMA | comic story | 4 | pencils: Hermann Mejía, Roberto Parada, James Warhola, Richard Williams; inks: Hermann Mejía, Roberto Parada, James Warhola, Richard Williams; colors: Hermann Mejía, Roberto Parada, James Warhola, Richard Williams | |
| 15 | Snappy Answers To Stupid Human Questions | comic story | 2 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee; colors: Ryan Flanders | |
| 16 | Great Monkeys In American History | comic story | 2 | script: Teresa Burns Parkhurst; pencils: Tom Fowler; inks: Tom Fowler | Goody Wendell; Miss Link; Corky McGoon; Chichi the Leader; Chokachikeel; Heavenly; Freeda Yasgur |
| 17 | Monkeybay | text article | 3 | script: Scott Maiko | |
| 18 | 9 Out of 10 Dentists Agree: MAD Won't Rot Your Teeth | promo (ad from the publisher) | 1 | pencils: Norman Mingo, Tom Bunk; inks: Norman Mingo, Tom Bunk; colors: Norman Mingo | Alfred E. Neuman |
| 19 | Spider Monkey vs. Spider Monkey | comic story | 2 | script: Peter Kuper; pencils: Peter Kuper; inks: Peter Kuper | Black Monkey; White Monkey |
| 20 | eHarmonkey | comic story | 1 | script: Teresa Burns Parkhurst; pencils: Teresa Burns Parkhurst; inks: Teresa Burns Parkhurst | |
| 21 | The Strip Club | comic story | 5 | script: John Kovaleski, Rob Harrell, Emily Flake, Scott Cunningham, Jason Yungbluth, Ted Rall; pencils: John Kovaleski, Rob Harrell, Emily Flake, Scott Cunningham, Jason Yungbluth, Ted Rall; inks: John Kovaleski, Rob Harrell, Emily Flake, Scott Cunningham, Jason Yungbluth, Ted Rall; letters: John Kovaleski, Rob Harrell, Emily Flake, Scott Cunningham, Jason Yungbluth, Ted Rall | |
| 22 | 10 Things You, As A Concerned Monkey, Can Do To Save The Environment | comic story | 2 | script: John Caldwell; pencils: John Caldwell; inks: John Caldwell | |
| 23 | How To Draw A Monkey | comic story | 1 | script: John Caldwell; pencils: John Caldwell; inks: John Caldwell | Skittles O'Shea (orangutan) |
| 24 | Bananas Republic Summer 2008 | comic story | 4 | script: Scott Maiko; pencils: Leonardo Rodriguez; inks: Leonardo Rodriguez | |
| 25 | What's The Worst Thing That Can Happen To Any Monkey? | activity | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | |
| 26 | Drawn-Out Dramas | comic story | 0 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |