| 0 | Special Hypnotic Issue of Mad | cover | 1 | letters: typeset | Alfred E. Neuman |
| 1 | - | letters page | 1 | script: Jerry De Fuccio | |
| 2 | When Politicians Do Television Commercials | comic story | 4 | script: Sol Weinstein, Donald Axe; pencils: Jack Rickard; inks: Jack Rickard | Richard Nixon; Pat Nixon; Madame Chiang Kai Shek; General Chiang Kai Shek; Lyndon Johnson; Nikita Khrushchev; George Wallace; Barry Goldwater |
| 3 | Drawn Out Dramas | cartoon | 0 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 4 | Three Hairy Stories | comic story | 2 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 5 | Mad's Snappy Answers to Those Old Cliches | comic story | 3 | script: Stan Hart; pencils: Paul Coker Jr.; inks: Paul Coker Jr. | |
| 6 | The Virginiaham | comic story | 5 | script: Lou Silverstone; pencils: Mort Drucker; inks: Mort Drucker | Lee J. Cobb [as Judge Barf]; Roberta Shore [as Becky Barf]; Doug McClure [as Tramputz]; James Drury [as The Virginiaham]; Lee Marvin [as The Guest Star]; Clu Gallagher [as Ricochet] |
| 7 | Boxing Foto-Plays | photo story | 3 | script: Arnie Kogen; pencils: UPI, AP/Wide World; inks: UPI, AP/Wide World | |
| 8 | Mad Interviews the Greeting Card Manufacturer of the Year | comic story | 4 | script: Stan Hart; pencils: Joe Orlando; inks: Joe Orlando | Frank Gifford [as Frank Giffurd]; Konrad Kupid |
| 9 | Spy Vs. Spy | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy; The White Spy |
| 10 | Let's Humanize Those Automated Machines | comic story | 2 | script: Stan Hart; pencils: Bob Clarke; inks: Bob Clarke | |
| 11 | The Lighter Side of Moving | comic story | 4 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 12 | A Celebrity's Wallet | comic story | 2 | script: Arnie Kogen; pencils: Bob Clarke; inks: Bob Clarke | |
| 13 | Spy Vs. Spy | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy; The White Spy |
| 14 | A Mad Guide to the Wildlife of Our American Highways | comic story | 3 | script: Frank Jacobs; pencils: Bob Clarke; inks: Bob Clarke | |
| 15 | Horror Movie Scenes We'd Like to See | cartoon | 2 | script: Don Edwing; pencils: Jack Davis; inks: Jack Davis | Frankenstein's monster; The Mummy; The Creature from the Black Lagoon; Dracula; King Kong |
| 16 | Spy Vs. Spy Vs. Spy | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy; The White Spy; The Gray Spy |
| 17 | The Rime of the Modern Surfer | comic story | 4 | script: Tom Koch; pencils: Don Martin; inks: Don Martin | |
| 18 | Football "In Depth" | comic story | 4 | script: Ronald Axe, Sol Weinstein; pencils: George Woodbridge; inks: George Woodbridge | Mel Hyndsite; Charlie Dittoe |
| 19 | What Wild Frenzy Will Future College Students Face? | illustration | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | |
| 20 | The Day They Forgot to Put the Top Down for the Hertz Commercial | photo story | 1 | pencils: Irving Schild; inks: Irving Schild; colors: Irving Schild | |