| 0 | Family Mad | cover | 1 | pencils: Mark Fredrickson; inks: Mark Fredrickson; colors: Mark Fredrickson | |
| 1 | - | table of contents | 1 | pencils: Al Jaffee; inks: Al Jaffee; colors: Al Jaffee; letters: Al Jaffee | |
| 2 | A Mad Look at Family Functions | comic story | 4 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés; colors: Carrie Strachan; letters: Sergio Aragonés | |
| 3 | The Trump Family Circus | comic story | 2 | script: Desmond Devlin; pencils: Tom Richmond; inks: Tom Richmond; colors: Tom Richmond | |
| 4 | - | comic story | 1.75 | script: Peter Kuper; pencils: Peter Kuper; inks: Peter Kuper; colors: Peter Kuper; letters: Peter Kuper | |
| 5 | - | comic story | 0.25 | script: Peter Kuper; pencils: Peter Kuper; inks: Peter Kuper; colors: Peter Kuper; letters: Peter Kuper | |
| 6 | Alfred E. Neuman's Family Tree | comic story | 3 | script: Tom Koch; pencils: Wally Wood; inks: Wally Wood | Nu Mun; Tut-Ankh-Nu-Men; Socrates Numanos; Nerd Numinus; Alfred The Hun; Alfred The Chicken-Harted; Johannes Nuemanberg; Christopher Numunbus; Amerigo Numanucci; Michaelanumano; Elder Neuman; Sir Isaac Neuman; Benjamin Neuman; General George Neuman; Paul Neuman; Patrick Neuman; Abraham Neuman; Jeffe |
| 7 | The Frog Prince | comic story | 1 | script: Don Edwing; pencils: Don Martin; inks: Don Martin | |
| 8 | The Royal Paininthebums | comic story | 5 | script: Arnie Kogen; pencils: Tom Richmond; inks: Tom Richmond | Alec Baldwin [as the narrator]; Gene Hackman [as Royal Paininthebum];Anjelica Huston [as Ethelfuel Paininthebum]; Ben Stiller [as Spaz Paininthebum]; Luke Wilson [as Rackety Paininthebum]; Gwyneth Paltrow [as Maggot Paininthebum]; Owen Wilson [as Eli Crash]; Bill Murray [as Raleigh St. Droopy]; Dann |
| 9 | The Mad Getting Married Primer | comic story | 3 | script: Dick DeBartolo; pencils: Jack Rickard; inks: Jack Rickard | |
| 10 | Mad Looks at Weddings | comic story | 3 | script: Don Edwing; pencils: Don Martin; inks: Don Martin | |
| 11 | Elephant In the Room | illustration | 2 | script: Desmond Devlin; pencils: Tom Richmond; inks: Tom Richmond; colors: Tom Richmond | |
| 12 | - | comic story | 1 | script: Antonio Prohías; pencils: Antonio Prohías; inks: Antonio Prohías | The Black Spy; The White Spy |
| 13 | 10 Warning Signs Your Family is Beyond Dysfunctional | comic story | 3 | script: John Caldwell; pencils: John Caldwell; inks: John Caldwell | |
| 14 | The Good, Bad, and Ugly of Having a Dysfunctional Dad | comic story | 2 | script: Ivan Ehlers; pencils: Ivan Ehlers; inks: Ivan Ehlers; colors: Ivan Ehlers | |
| 15 | Sibling Misery Is... | comic story | 3 | script: Paul Peter Porges; pencils: Paul Coker; inks: Paul Coker | |
| 16 | Malcontent in the Muddle | comic story | 6 | script: Desmond Devlin; pencils: Tom Richmond; inks: Tom Richmond | Frankie Muniz [as Malcontent]; Jane Kaczmarek [as Mom]; Bryan Cranston [as Howl]; Christopher Masterson [as Frantic]; Erik Per Sullivan [as Gooey]; Timothy Q. Mouse (cameo); Justin Berfield [as Reek]; Craig Lamar Traylor [as Skeevy]; Alfred E. Neuman (cameo) |
| 17 | Sibling Rivalry | comic story | 1 | script: Mike Carlin; pencils: Hermann Mejía; inks: Hermann Mejía; colors: Hermann Mejía | |
| 18 | One Fine Evening During Prime Time | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin | |
| 19 | The Lighter Side of... Family Gatherings | comic story | 5 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | |
| 20 | The Family from Hell: Home for the Holidays | comic story | 2 | script: Brockton McKinney; pencils: Gideon Kendall; inks: Gideon Kendall; colors: Gideon Kendall | |
| 21 | Christmas Carols for Dysfunctional Families | comic story | 3 | script: Frank Jacobs; pencils: Tom Bunk; inks: Tom Bunk | |
| 22 | - | comic story | 1 | script: Peter Kuper; pencils: Peter Kuper; inks: Peter Kuper; colors: Peter Kuper; letters: Peter Kuper | |
| 23 | Dysfunctional Family Circus | comic story | 1 | script: Desmond Devlin; pencils: George Woodbridge; inks: George Woodbridge | |
| 24 | What Is Yet Another Cause of Broken Homes In the USA? | activity | 1 | script: Johnny Sampson; pencils: Johnny Sampson; inks: Johnny Sampson; colors: Johnny Sampson | |
| 25 | One Evening at Home | comic story | 1 | script: Don Martin; pencils: Don Martin; inks: Don Martin; colors: Carrie Strachan | |