| 0 | Attack of the 20 Dumbest 2018 | cover | 1 | pencils: Michael Koelsch; inks: Michael Koelsch; colors: Michael Koelsch | |
| 1 | - | table of contents | 2 | letters: typeset | |
| 2 | A Listless Story | comic story | 6 | script: Desmond Devlin; pencils: Tom Richmond; inks: Tom Richmond; colors: Tom Richmond | |
| 3 | A Mad Look at After Christmas | comic story | 4 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés; colors: Tom Luth; letters: Sergio Aragonés | |
| 4 | The Mad 20 Dumbest People, Events, & Things of 2018 | illustration | 1 | letters: typeset | |
| 5 | 1 Hollywood Harassers | illustration | 2 | script: Mary Trainor; pencils: Terry Wolfinger; inks: Terry Wolfinger; colors: Terry Wolfinger | |
| 6 | 2 White House Corruption | illustration | 1 | script: Tammy Golden; pencils: Paul Wee; inks: Paul Wee; colors: Paul Wee | |
| 7 | 3 Detention Centers Put Children In Cages | illustration | 1 | script: Casey Boyd; pencils: Ed Steckley; inks: Ed Steckley; colors: Ed Steckley | |
| 8 | 4 Guilty of Being Black | illustration | 1 | script: Casey Boyd; pencils: Timothy Shamey; inks: Timothy Shamey; colors: Timothy Shamey | |
| 9 | 5 Michelle Wolf Hosts Correspondent's Dinner | illustration | 1 | script: Tammy Golden; pencils: Scott Bricher; inks: Scott Bricher; colors: Scott Bricher | |
| 10 | 6 Marco Rubio Debates Parkland Students | comic story | 1 | script: Matt Cohen; pencils: Dario Brizuela; inks: Dario Brizuela; colors: Dario Brizuela | |
| 11 | 7 A Nuclear Screw-Up | illustration | 1 | script: Desmond Devlin; pencils: Mark Fredrickson; inks: Mark Fredrickson; colors: Mark Fredrickson | |
| 12 | 8 FLOTUS Visits Captured Kids On the Border | illustration | 1 | script: Wilcox Deckert; pencils: Wilcox Deckert; inks: Wilcox Deckert; colors: Wilcox Deckert | |
| 13 | 9 Rosanne Shifts Blame for Racist Rant | comic story | 1 | script: Dick DeBartolo; pencils: Scott Anderson; inks: Scott Anderson; colors: Scott Anderson | |
| 14 | 10 Poddy-Mouthed Kids | illustration | 1 | script: Brockton McKinney; pencils: Sarah Chalek; inks: Sarah Chalek; colors: Sarah Chalek | |
| 15 | 11 Trump Panders to Putin at Helsinki Meeting | illustration | 1 | script: Teresa Burns Parkhurst; pencils: Paul Shipper; inks: Paul Shipper; colors: Paul Shipper | |
| 16 | 12 Thai Cave Save | illustration | 2 | script: R. Wilcox Deckert; pencils: Nathan Kane; inks: Nathan Kane; colors: Nathan Kane | |
| 17 | 13 Protesters Burning Nike Products | illustration | 1 | script: Casey Boyd; pencils: Gideon Kendall; inks: Gideon Kendall; colors: Gideon Kendall | |
| 18 | 14 Paul Manafort Flips | illustration | 1 | script: Desmond Devlin; pencils: Dean MacAdam; inks: Dean MacAdam; colors: Dean MacAdam | |
| 19 | 15 Doritos Pitches Chips for Ladies | illustration | 1 | script: Allie Goertz; pencils: Mike Loew; inks: Mike Loew; colors: Mike Loew | |
| 20 | 16 Toys "R" Us Comes Back From the Dead | illustration | 1 | script: Dan Telfer; pencils: Chris Wahl; inks: Chris Wahl; colors: Chris Wahl | |
| 21 | 17 Brett Kavanaugh's Supreme Court Hearings | illustration | 1 | script: Teresa Burns Parkhurst; pencils: Teresa Burns Parkhurst; inks: Teresa Burns Parkhurst; colors: Teresa Burns Parkhurst | |
| 22 | 18 Trump's Space Force | illustration | 1 | script: Brockton McKinney; pencils: Sam Sisco; inks: Sam Sisco; colors: Sam Sisco | |
| 23 | 19 Sarah Huckabee Sanders | illustration | 1 | script: Kit Lively; pencils: Mike Loew; inks: Mike Loew; colors: Mike Loew | |
| 24 | 20 Mad 20 Fold-In | activity | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee; colors: Al Jaffee | |
| 25 | The Lighter Side of the War on Christmas | comic story | 2 | script: Tammy Golden; pencils: Jon Adams; inks: Jon Adams; colors: Jon Adams | |
| 26 | Tanks for the Grenades | comic story | 2 | script: Peter Kuper; pencils: Peter Kuper; inks: Peter Kuper; colors: Peter Kuper; letters: Peter Kuper | |
| 27 | Mega Movement! | illustration | 1 | script: Glenn Barr; pencils: Glenn Barr; inks: Glenn Barr; colors: Glenn Barr | |
| 28 | Potrzebie Comics | illustration | 1 | pencils: Kerry Callen; inks: Kerry Callen; colors: Kerry Callen | |
| 29 | It's a Wonderful Death | comic story | 3 | script: Luke McGarry; pencils: Luke McGarry; inks: Luke McGarry; colors: Luke McGarry | |
| 30 | Lukey & Mukey | comic story | 3 | script: Bob Fingerman; pencils: Bob Fingerman; inks: Bob Fingerman; colors: Bob Fingerman | |
| 31 | Holiday Party | comic story | 3 | script: George A. Escobar, Bob Lizarraga; pencils: Bob Lizarraga; inks: Bob Lizarraga; colors: Bob Lizarraga | |
| 32 | Christmas with the Chancers | comic story | 1 | script: Luke McGarry; pencils: Luke McGarry; inks: Luke McGarry; colors: Luke McGarry | |
| 33 | MILF on the Shelf | illustration | 0.25 | script: Kit Lively; pencils: Rick Tulka; inks: Rick Tulka; colors: Rick Tulka | |
| 34 | Inconvenience Store | cartoon | 0.25 | script: Peter Kuper; pencils: Peter Kuper; inks: Peter Kuper; colors: Peter Kuper; letters: Peter Kuper | |
| 35 | Bumper Stickers of Despair | cartoon | 0.5 | script: Kenny Keil | |
| 36 | Least-Popular Apps on the Market | text story | 0.5 | script: Mike Armstrong; pencils: Sarah Chalek; inks: Sarah Chalek; colors: Sarah Chalek | |
| 37 | Sad Santa | cartoon | 0.25 | script: Kit Lively; pencils: Lance Hansen; inks: Lance Hansen; colors: Lance Hansen | |
| 38 | - | cartoon | 0.25 | script: Johnny Sampson; pencils: Johnny Sampson; inks: Johnny Sampson; colors: Johnny Sampson | |
| 39 | - | letters page | 2 | script: Alex Taffer | |
| 40 | - | text story | 1 | script: John Ungaro; pencils: Mike Loew; inks: Mike Loew; colors: Mike Loew | |
| 41 | - | comic story | 0.5 | script: Mike Holmes; pencils: Mike Holmes; inks: Mike Holmes; colors: Mike Holmes | |
| 42 | - | statement of ownership | 0.25 | letters: typeset | |