| 0 | - | cover | 1 | pencils: Esad Ribić; inks: Esad Ribić; colors: Esad Ribić | Thing; Hulk [Bruce Banner] |
| 1 | - | cover | 1 | pencils: Esad Ribić; inks: Esad Ribić; colors: Esad Ribić | Thing; Hulk [Bruce Banner] |
| 2 | The Honeymoon Crasher | comic story | 20 | script: Dan Slott; pencils: Sean Izaakse; inks: Sean Izaakse; colors: Marcio Menyz; letters: VC's Joe Caramagna | Fantastic Four [Thing; Mr. Fantastic; Invisible Woman; Human Torch]; Hulk [Bruce Banner]; Puppet Master; Alicia Masters Grimm; Valeria Richards; Franklin Richards |
| 3 | - | cover reprint (on interior page) | 1 | pencils: Esad Ribić; inks: Esad Ribić; colors: Esad Ribić | Thing |
| 4 | The Fight of Your Life | comic story | 20 | script: Dan Slott; pencils: Sean Izaakse; inks: Sean Izaakse; colors: Marcio Menyz; letters: VC's Joe Caramagna | Fantastic Four [Thing; Mr. Fantastic; Invisible Woman; Human Torch]; Hulk; Alicia Masters Grimm; Puppet Master |
| 5 | - | cover reprint (on interior page) | 1 | pencils: Esad Ribić; inks: Esad Ribić; colors: Esad Ribić | Thing [Ben Grimm]; Human Torch [Johnny Storm] |
| 6 | 4 Yancy Street | comic story | 30 | script: Gerry Duggan; pencils: Greg Smallwood, Mark Bagley, Luciano Vecchio, Pere Pérez; inks: Greg Smallwood, Mark Bagley, Luciano Vecchio, Pere Pérez; colors: Greg Smallwood, Erick Arciniega; letters: VC's Joe Caramagna | Fantastic Four [Mr. Fantastic [Reed Richards]; Invisible Woman [Susan Storm Richards]; Thing [Ben Grimm]; Human Torch [Johnny Storm]]; Terrible Trio [Bull Brogin; Yogi Dakor; Handsome Harry Phillips]; Daniel Grimm (flashback); Rachel Grimm (cameo flashback); Jake Grimm (cameo flashback); Doctor Doom |
| 7 | - | cover reprint (on interior page) | 1 | pencils: Kim Jacinto; inks: Kim Jacinto; colors: Rain Beredo | Fantastic Four [Mr. Fantastic [Reed Richards]; the Thing [Ben Grimm]; Invisible Woman [Susan Storm]; the Human Torch [Johnny Storm]]; Annihilus; the Fantastix (inset) |
| 8 | Ethical Dilemmas in Modern Science | comic story | 22 | script: Mike Carey; pencils: Stefano Caselli; inks: Stefano Caselli; colors: Erick Arciniega; letters: VC's Cory Petit | Fantastic Four [the Thing [Ben Grimm]; the Human Torch [Johnny Storm]; Mr. Fantastic [Reed Richards]; Invisible Woman [Susan Storm]]; Annihilus (flashback); Blastaar; Korux |
| 9 | What Are the Fantastix For? | comic story | 10 | script: Ryan North; pencils: Steve Uy; inks: Steve Uy; colors: Steve Uy; letters: VC's Cory Petit | The Fantastix [2-D; Hope; Iceberg; Ms. Fantastix]; Mister Fantastic [Reed Richards]; Skrulltastic One |
| 10 | #13, Pages 12-13 Sketches and Final Art | illustration | 2 | pencils: Tom Brevoort, Sean Izaakse; inks: Sean Izaakse | |
| 11 | #12 Carnage-ized Variant | cover reprint (on interior page) | 1 | pencils: Patch Zircher; inks: Patch Zircher; colors: Jason Keith | Fantastic Four [Mister Fantastic; Invisible Woman; Thing; Human Torch] (all as Carnage) |
| 12 | - | cover reprint (on interior page) | 1 | pencils: Gerald Parel; inks: Gerald Parel; colors: Gerald Parel | Fantastic Four [Mister Fantastic; Human Torch; Thing; Invisible Woman]; Doctor Doom |
| 13 | #13 Marvel 80th Anniversary Variant | cover reprint (on interior page) | 1 | pencils: Nick Bradshaw, Mike McKone; inks: Nick Bradshaw, Mike McKone; colors: Edgar Delgado | Human Torch [Johnny Storm]; Valkyrie [Jane Foster]; Loki; Wolverine [Logan]; Thor; Wasp [Nadia Van Dyne]; Hawkeye [Clint Barton]; Daredevil [Matt Murdock]; Gamora; Cyclops [Scott Summers]; Scarlet Witch [Wanda Maximoff]; Spider-Man [Miles Morales]; Vision; Jean Grey; Thing [Ben Grimm]; Storm [Ororo |
| 14 | - | cover reprint (on interior page) | 1 | pencils: Stonehouse; inks: Stonehouse; colors: Stonehouse | Thing [Ben Grimm] |
| 15 | 4 Yancy Street Hidden Gem Variant | cover reprint (on interior page) | 1 | pencils: Jack Kirby; inks: Jack Kirby; colors: Chris Sotomayor | Thing [Ben Grimm] |
| 16 | - | cover reprint (on interior page) | 1 | pencils: Tom Raney; inks: Tom Raney; colors: Dave McCaig | The Thing [Ben Grimm] |
| 17 | - | cover reprint (on interior page) | 1 | pencils: Mico Suayan; inks: Mico Suayan; colors: Rain Beredo | Fantastic Four [Mr. Fantastic [Reed Richards]; Invisible Woman [Susan Storm]; the Thing [Ben Grimm]; the Human Torch [Johnny Storm]] |