| 0 | - | cover | 1 | pencils: Nick Bradshaw; inks: Nick Bradshaw; colors: John Rauch | Mr. Fantastic; Invisible Woman; Thing; Human Torch; Sidearm; Sky; Citadel |
| 1 | #14 Immortal Variant | cover reprint (on interior page) | 0.5 | pencils: Tom Raney; inks: Tom Raney; colors: Rachelle Rosenberg | Mister Fantastic [Reed Richards] |
| 2 | #14 Immortal Variant | cover reprint (on interior page) | 0.5 | pencils: Christian Ward; inks: Christian Ward; colors: Christian Ward | Invisible Woman [Susan Richards] |
| 3 | - | cover reprint (on interior page) | 1 | pencils: Mike Deodato Jr.; inks: Mike Deodato Jr.; colors: Romulo Fajardo Jr. | Thing; Human Torch; Mr. Fantastic; Invisible Woman |
| 4 | Point of Origin Part One: Wanderlust | comic story | 20 | script: Dan Slott; pencils: Paco Medina; inks: Paco Medina; colors: Jesus Aburtov; letters: VC's Joe Caramagna | Fantastic Four [Mr. Fantastic; Invisible Woman; Human Torch; Thing]; Valeria Richards; Franklin Richards; Alicia Masters Grimm; Colonel Duchman; Captain Sanders; H.E.R.B.I.E. |
| 5 | - | cover reprint (on interior page) | 1 | pencils: Nick Bradshaw; inks: Nick Bradshaw; colors: John Rauch | Mr. Fantastic; Thing; Invisible Woman; Human Torch |
| 6 | Point of Origin Part Two: The Invasion | comic story | 20 | script: Dan Slott; pencils: Paco Medina; inks: Bob Quinn; colors: Jesus Aburtov; letters: VC's Joe Caramagna | Fantastic Four [Thing; Human Torch; Invisible Woman; Mr. Fantastic]; Overseer; Unparalleled [Kor; Kaylo; Citadel; Sky; Sidearm; Elementa; Astrobelter] |
| 7 | - | cover reprint (on interior page) | 1 | pencils: Valerio Schiti; inks: Valerio Schiti; colors: Richard Isanove | Fantastic Four [Mr. Fantastic; Invisible Woman; Thing; Human Torch]; The Unparalleled [Citadel; Kor; Kaylo; Sidearm; Sky; Elementa; Astro-Belter] |
| 8 | - | cover reprint (on interior page) | 1 | pencils: Nick Bradshaw; inks: Nick Bradshaw; colors: John Rauch | Thing |
| 9 | Point of Origin Part Three: Fantastic Planet | comic story | 20 | script: Dan Slott; pencils: Sean Izaakse; inks: Sean Izaakse; colors: Marcio Menyz; letters: VC's Joe Caramagna | Fantastic Four [Thing; Human Torch; Invisible Woman; Mr. Fantastic]; Unparalleled [Sky; Citadel; Astrobelter; Sidearm; Kaylo; Kor; Elementa]; Overseer; Big King Scrum |
| 10 | #14 Immortal Variant | cover reprint (on interior page) | 0.5 | pencils: Mike McKone; inks: Mike McKone; colors: Rachelle Rosenberg | Thing [Ben Grimm] |
| 11 | #14 Immortal Variant | cover reprint (on interior page) | 0.5 | pencils: InHyuk Lee; inks: InHyuk Lee; colors: InHyuk Lee | Human Torch [Johnny Storm] |
| 12 | - | cover reprint (on interior page) | 1 | pencils: Nick Bradshaw; inks: Nick Bradshaw; colors: John Rauch | Human Torch; Sky |
| 13 | Point of Origin Part Four: Secret Agenda | comic story | 20 | script: Dan Slott; pencils: Luciano Vecchio, Carlos Magno, Bob Quinn, Sean Izaakse; inks: Luciano Vecchio, Carlos Magno, Bob Quinn, Sean Izaakse; colors: Erick Arciniega; letters: VC's Travis Lanham | Fantastic Four [Thing; Invisible Woman; Mr. Fantastic; Human Torch]; Overseer; Unparalleled [Elementa; Kaylo; Kor; Sky; Sidearm; Citadel; Astrobelter]; Big King Scrum |
| 14 | - | cover reprint (on interior page) | 1 | pencils: Nick Bradshaw; inks: Nick Bradshaw; colors: John Rauch | Mr. Fantastic; Invisible Woman; Thing; Human Torch; Sidearm; Sky; Citadel |
| 15 | Point of Origin Part Five: Worldbreakers | comic story | 20 | script: Dan Slott; pencils: Paco Medina, Francesco Manna, Carlos Magno; inks: Paco Medina, Francesco Manna, Carlos Magno; colors: Erick Arciniega; letters: VC's Travis Lanham | Fantastic Four [Invisible Woman; Mr. Fantastic; Human Torch; Thing]; Overseer; Unparalleled [Kaylo; Kor; Sky; Sidearm; Elementa; Astrobelter; Citadel]; Big King Scrum |
| 16 | #14 Immortal Variant | cover reprint (on interior page) | 0.5 | pencils: Ryan Brown; inks: Ryan Brown; colors: Ryan Brown | Doctor Doom [Victor Von Doom] |
| 17 | #17 Venom Island Variant | cover reprint (on interior page) | 0.25 | pencils: Carlos Gómez; inks: Carlos Gómez; colors: Jesus Aburtov | Fantastic Four [Human Torch [Johnny Storm]; Mr. Fantastic [Reed Richards]; Invisible Woman [Susan Storm]; the Thing [Ben Grimm]] |
| 18 | #17 2020 Variant | cover reprint (on interior page) | 0.25 | pencils: Khoi Pham; inks: Khoi Pham; colors: Morry Hollowell | Thing |
| 19 | - | cover reprint (on interior page) | 1 | pencils: Nick Bradshaw; inks: Nick Bradshaw; colors: Marcio Menyz | Mr. Fantastic; Overseer; Human Torch; Invisible Woman; Thing |
| 20 | Point of Origin Part Six: Four Gone Conclusion | comic story | 20 | script: Dan Slott; pencils: Sean Izaakse; inks: Sean Izaakse; colors: Marcio Menyz, Erick Arciniega; letters: VC's Joe Caramagna | Fantastic Four [Thing; Mr. Fantastic; Invisible Woman; Human Torch]; Overseer [Revos]; Unparalleled [Sky; Kaylo; Kor; Citadel; Sidearm; Elementa; Astrobelter]; Big King Scrum [Krumson]; Wyatt Wingfoot; Dr. Sara Heart; Mole Man (cameo); Alicia Masters Grimm (cameo); Hiram Scheckerberg (cameo) |
| 21 | - | cover reprint (on interior page) | 1 | pencils: Nick Bradshaw; inks: Nick Bradshaw; colors: John Rauch | Human Torch; Mole Man; Wyatt Wingfoot; Sky |
| 22 | Welcoming Party | comic story | 20 | script: Dan Slott; pencils: Paco Medina; inks: Paco Medina; colors: Jesus Aburtov; letters: VC's Joe Caramagna | Fantastic Four [Human Torch; Invisible Woman; Mr. Fantastic; Thing]; Valeria Richards; Franklin Richards; Sky; Wyatt Wingfoot; Alicia Masters-Grimm; Mole Man; Dr. Sara Heart |
| 23 | Sketches | illustration | 2 | pencils: Sean Izaakse; inks: Sean Izaakse | Elementa; Citadel; Kor; Kaylo; Belter; Sidearm; Sky |
| 24 | - | text story | 1 | script: Dan Slott | |
| 25 | #15 Mary Jane Variant | cover reprint (on interior page) | 1 | pencils: J. Scott Campbell; inks: J. Scott Campbell; colors: Sabine Rich | Fantastic Four [Mr. Fantastic; Invisible Woman; Thing; Human Torch]; Mary Jane Watson |
| 26 | #16 2099 Variant | cover reprint (on interior page) | 0.25 | pencils: Greg Land; inks: Greg Land; colors: Frank D'Armata | Fantastic Four [Mister Fantastic; Human Torch; Thing; Invisible Woman] |
| 27 | #18 Marvels X Variant | cover reprint (on interior page) | 0.25 | pencils: Greg Smallwood; inks: Greg Smallwood; colors: Greg Smallwood | Thing [Ben Grimm] |
| 28 | #19 Gwen Stacy Variant | cover reprint (on interior page) | 0.25 | pencils: John Tyler Christopher; inks: John Tyler Christopher; colors: John Tyler Christopher | Gwen Stacy; Thing [Ben Grimm] |
| 29 | #20 Spider-Woman Variant | cover reprint (on interior page) | 0.25 | pencils: Ema Lupacchino; inks: Ema Lupacchino; colors: Jason Keith | Fantastic Four [Mister Fantastic; Invisible Woman; Thing; Human Torch]; Spider-Woman [Jessica Drew] |