| 0 | Brand New Day | cover | 1 | pencils: John Romita Jr.; inks: Klaus Janson; colors: Dean White | Spider-Man [Peter Parker]; Anti-Venom [Eddie Brock] |
| 1 | Brand New Day | credits, title page | 1 | letters: typeset | Spider-Man [Peter Parker] |
| 2 | Spider-Man | table of contents | 2 | letters: typeset | Spider-Man [Peter Parker] |
| 3 | - | cover reprint (on interior page) | 1 | pencils: Greg Land; inks: Jay Leisten; colors: Frank D'Armata | Spider-Man [Peter Parker] |
| 4 | - | foreword, introduction, preface, afterword | 1 | | |
| 5 | Death of a Wise Guy | comic story | 18 | script: Joe Kelly; pencils: Chris Bachalo; inks: Tim Townsend; colors: Antonio Fabela, Chris Bachalo; letters: VC, Cory Petit | Hammerhead; Spider-Man [Peter Parker] |
| 6 | Birthday Boy | comic story | 8 | script: Zeb Wells; pencils: Patrick Olliffe; inks: Serge LaPointe; colors: Rain Beredo; letters: VC, Cory Petit | Spider-Man [Peter Parker]; Harry Osborn; Trapster; Jay Hunter |
| 7 | Breakdown! | cover reprint (on interior page) | 1 | pencils: Phil Jimenez; inks: Andy Lanning | Spider-Man [Peter Parker] |
| 8 | Cops, Crooks and Capers! | recap | 1 | letters: typeset | |
| 9 | Kraven's First Hunt Part One To Squash a Spider! | comic story | 22 | script: Marc Guggenheim; pencils: Phil Jimenez; inks: Andy Lanning; colors: Chris Chuckry; letters: Virtual Calligraphy, Cory Petit | Spider-Man [Peter Parker]; Daredevil [Matt Murdock] (guest); Vin Gonzales [also as Spider-Man] (guest); Harry Osborn (guest); Fracture (villain); Kraven [Ana Kravinoff] (villain) |
| 10 | The Web-Head without Fear! | cover reprint (on interior page) | 1 | pencils: Phil Jimenez; inks: Andy Lanning | Daredevil [Peter Parker] |
| 11 | Kraven’s First Hunt Part Two Identity Crisis! | comic story | 22 | script: Marc Guggenheim; pencils: Phil Jimenez; inks: Mark Pennington; colors: Chris Chuckry, Jeromy Cox; letters: Virtual Calligraphy, Cory Petit | Daredevil [Peter Parker]; Vin Gonzales [as Spider-Man] (guest); Matt Murdock [Daredevil] (guest); Kraven [Ana Kravinoff] (villain); Vermin (villain) |
| 12 | - | cover reprint (on interior page) | 1 | pencils: Phil Jimenez; inks: Phil Jimenez | Daredevil [Peter Parker]; Vin Gonzales [Spider-Man]; Kraven [Ana Kravinoff] |
| 13 | Kraven's First Hunt Part Three Legacy | comic story | 22 | script: Marc Guggenheim; pencils: Phil Jimenez; inks: Andy Lanning; colors: Chris Chuckry; letters: Virtual Calligraphy, Cory Petit | Spider-Man [also as Daredevil]; Vin Gonzales [as Spider-Man]; Harry Osborn; Lily Hollister; Carlie Cooper; Kraven [Ana Kravinoff] (villain); Vermin (villain); Sasha Nikolaevich (villain); Kraven [Sergei Kravinoff] (cameo flashback) |
| 14 | - | cover reprint (on interior page) | 1 | pencils: John Romita Jr.; inks: Klaus Janson; colors: Dean White | Spider-Man [Peter Parker] |
| 15 | New Ways to Die Part One: Back with Vengeance | comic story | 28 | script: Dan Slott; pencils: John Romita Jr.; inks: Klaus Janson; colors: Dean White; letters: Virtual Calligraphy, Cory Petit | Spider-Man [Peter Parker]; May Parker; Harry Osborn; Norman Osborn [Green Goblin (flashback)]; Ben Urich; Robbie Robertson; Martin Li; Eddie Brock; Betty Brant; Dexter Bennett; Randall Crowne; Sally Floyd; Thunderbolts [Songbird; Venom [Mac Gargan]; Bullseye; Radioactive Man] (guests); Menace (villa |
| 16 | Fifth Stage | comic story | 10 | script: Mark Waid; pencils: Adi Granov; inks: Adi Granov; colors: Adi Granov; letters: Virtual Calligraphy, Cory Petit | Eddie Brock [also as Venom in flashback]; Aunt May Parker (guest); Martin Li (guest); Spider-Man (cameo flashback) |
| 17 | - | cover reprint (on interior page) | 1 | pencils: John Romita Jr.; inks: Klaus Janson; colors: Dean White | Spider-Man [Peter Parker]; Norman Osborn; Songbird; Venom [Mac Gargan]; Radioactive Man |
| 18 | New Ways to Die Part Two: The Osborn Supremacy | comic story | 22 | script: Dan Slott; pencils: John Romita Jr.; inks: Klaus Janson; colors: Dean White; letters: Virtual Calligraphy, Cory Petit | Spider-Man [Peter Parker]; Aunt May Parker (guest); Vin Rodrigues (guest); Harry Osborn (guest); Norman Osborn (guest); Martin Li (guest); Eddie Brock [as Anti-Venom in cameo] (guest); Ben Urich (guest); Dexter Bennett (guest); Carlie Cooper (guest); Lily Hollister; Thunderbolts [Songbird; Venom [Ma |
| 19 | Apes Variant | cover reprint (on interior page) | 1 | pencils: Mike McKone; inks: Mike McKone | Monky Spider-Man; Monkey Venom |
| 20 | - | cover reprint (on interior page) | 1 | pencils: John Romita Jr.; inks: Klaus Janson; colors: Dean White | Spider-Man [Peter Parker]; Anti-Venom [Eddie Brock]; Venom [Mac Gargan] |
| 21 | New Ways to Die Part Three: The Killer Cure | comic story | 24 | script: Dan Slott; pencils: John Romita Jr.; inks: Klaus Janson; colors: Dean White; letters: Virtual Calligraphy, Cory Petit | Spider-Man [Peter Parker]; Aunt May Parker; Vin Gonzales; Norman Osborn [also as Green Goblin in flashback]; Martin Li; Anti-Venom [Eddie Brock]; Ben Urich; Sally Floyd; Robbie Robertson; Bill Hollister; Venom [Mac Gargan]; Bullseye; Menace (villain); Enforcers [Montana; Ox; Fancy Dan] (cameo flashb |
| 22 | - | cover reprint (on interior page) | 1 | pencils: John Romita Jr.; inks: Klaus Janson; colors: Dean White | Spider-Man [Peter Parker]; Green Goblin [Norman Osborn] |
| 23 | New Ways to Die Part Four: Opposites Attack | comic story | 23 | script: Dan Slott; pencils: John Romita Jr.; inks: Klaus Janson; colors: Dean White; letters: Virtual Calligraphy, Cory Petit | Spider-Man [Peter Parker]; Aunt May Parker; Vin Gonzales; Harry Osborn; Norman Osborn [also as Green Goblin in flashback]; Anti-Venom [Eddie Brock]; Ben Urich; Sally Floyd; Betty Brant; Carlie Cooper; Lily Hollister; Bill Hollister; Randall Crowne; Thunderbolts [Songbird; Venom [Mac Gargan]; Bullsey |
| 24 | - | cover reprint (on interior page) | 1 | pencils: John Romita Jr.; inks: John Romita Jr.; colors: Dean White | Bullseye |
| 25 | New Ways to Die Part Five: Easy Targets | comic story | 23 | script: Dan Slott; pencils: John Romita Jr.; inks: Klaus Janson; colors: Dean White; letters: Virtual Calligraphy, Cory Petit | Spider-Man [Peter Parker]; Aunt May Parker (guest); Vin Gonzales (guest); Harry Osborn (guest); Green Goblin [Norman Osborn] (guest); Anti-Venom [Eddie Brock] (guest); Ben Urich (guest); Sally Floyd (guest); Betty Brant (guest); Lily Hollister (guest); Thunderbolts [Songbird; Venom [Mac Gargan; also |
| 26 | - | cover reprint (on interior page) | 1 | pencils: John Romita Jr.; inks: Klaus Janson; colors: Dean White | Green Goblin [Norman Osborn] |
| 27 | New Ways to Die Part Six: Weapons of Self Destruction | comic story | 28 | script: Dan Slott; pencils: John Romita Jr.; inks: Klaus Janson; colors: Dean White; letters: Virtual Calligraphy, Cory Petit | Spider-Man [Peter Parker]; Aunt May Parker; Green Goblin [Norman Osborn]; Anti-Venom [Eddie Brock]; Ben Urich; Sally Floyd; Lily Hollister; Betty Brant; Martin Li; Thunderbolts [Songbird; Venom [Mac Gargan; also as Scorpion]; Bullseye; Radioactive Man] |
| 28 | - | cover reprint (on interior page) | 1 | pencils: Barry Kitson; inks: Barry Kitson | Flash Thompson; Spider-Man [Peter Parker] |
| 29 | - | comic story | 22 | script: Marc Guggenheim; pencils: Barry Kitson; inks: Mark Farmer; colors: Studio F, Antonio Fabela; letters: VC, Cory Petit | Flash Thompson; Gen. Fazekas; Santos; Doctor Doom |
| 30 | The Amazing Spider-Mail | letters page | 1 | script: Steve Wacker | |
| 31 | - | cover reprint (on interior page) | 1 | pencils: Chris Bachalo; inks: Tim Townsend; colors: Chris Bachalo | Spider-Man [Peter Parker]; Hammerhead |
| 32 | Family Ties | comic story | 23 | script: Joe Kelly; pencils: Chris Bachalo; inks: Tim Townsend; colors: Chris Bachalo, Antonio Fabela; letters: VC, Cory Petit | S.I.M.O.N.; Greta; Spider-Man [Peter Parker]; Hammerhead; Mr. Negative; Ben Urich; Norah Winters; Dunk; May Parker |
| 33 | - | cover reprint (on interior page) | 1 | pencils: Chris Bachalo; inks: Tim Townsend; colors: Chris Bachalo | Hammerhead; Spider-Man [Peter Parker] |
| 34 | Family Ties Part 2 | comic story | 22 | script: Joe Kelly; pencils: Chris Bachalo; inks: Chris Bachalo, Jaime Mendoza, Tim Townsend, Al Vey; colors: Chris Bachalo, Antonio Fabela; letters: VC, Cory Petit | Doctor Tramma, Vin Gonzales, Hammerhead, Martin Li, Mister Negative, Peter Parker, Spider-Man, Ben Urich, Norah Winters |
| 35 | - | cover reprint (on interior page) | 1 | pencils: Paolo Rivera; inks: Paolo Rivera | Spider-Man [Peter Parker]; Punisher [Frank Castle] |
| 36 | Old Huntin' Buddies | comic story | 18 | script: Zeb Wells; pencils: Paolo Rivera; inks: Paolo Rivera; colors: Javier Rodríguez, Dean White; letters: VC, Cory Petit | Punisher [Frank Castle]; Carlo; Moses Magnum; Spider-Man [Peter Parker] |
| 37 | J. Jonah Jameson! I Name Thee Murderer! | comic story | 6 | script: Joe Kelly; pencils: Barry Kitson; inks: Mark Farmer; colors: Dean White; letters: VC, Cory Petit | the Bookie; J. Jonah Jameson |
| 38 | Old Huntin' Buddies Part 2 | comic story | 14 | script: Zeb Wells; pencils: Paolo Rivera; inks: Paolo Rivera; colors: Javier Rodríguez, Dean White; letters: VC, Cory Petit | Spider-Man [Peter Parker]; Moses Magnum; Punisher [Frank Castle] |
| 39 | Jackpot | cover reprint (on interior page) | 1 | pencils: Mike McKone; inks: Andy Lanning; colors: Jeromy Cox | Jackpot; Harry Osborn; Lily; Super Skrull |
| 40 | Brand New Secret Invasion [Part 1] | comic story | 22 | script: Brian Reed; pencils: Marco Santucci; inks: Mark Pennington; colors: Jeromy Cox; letters: Jared K. Fletcher | Jackpot; Harry Osborn (guest); Lily (guest); Joe Robertson (guest); Betty Brant (guest); Vin Gonzalez (guest); Dexter Bennett (guest); Super Skrulls (villains) |
| 41 | Jackpot | cover reprint (on interior page) | 1 | pencils: Mike McKone; inks: Andy Lanning; colors: Jeromy Cox | Jackpot; Super Skrull |
| 42 | Brand New Secret Invasion Part 2 | comic story | 23 | script: Brian Reed; pencils: Marco Santucci; inks: Mark Pennington; colors: Jeromy Cox; letters: Jared K. Fletcher | Jackpot; Harry Osborn (guest); Lily (guest); Joe Robertson (guest); Betty Brant (guest); Vin Gonzalez (guest); Dexter Bennett (guest); Super Skrulls (villains); Menace (villain); Spider-Man (cameo) |
| 43 | Jackpot | cover reprint (on interior page) | 1 | pencils: Mike McKone; inks: Andy Lanning; colors: Jeromy Cox | Jackpot; Skrull versions of Dr. Octopus; Electro; Scorpion; Vulture; Sandman; Kingpin; Shocker |
| 44 | Part Three of...Brand New Secret Invasion | comic story | 23 | script: Brian Reed; pencils: Marco Santucci; inks: Mark Pennington, Dave Meikis, Victor Olazaba; colors: Jeromy Cox, Chris Sotomayor, John Kalisz; letters: Jared K. Fletcher | Jackpot; Spider-Man (guest); Harry Osborn (guest); Lily (guest); Joe Robertson (guest); Betty Brant (guest); Vin Gonzalez (guest); Dexter Bennett (guest); Super Skrulls (villains); Menace (villain); Mr. Fantastic (cameo); Ares (cameo); Daredevil (cameo); Iron Fist (cameo); Nick Fury (cameo); Wasp (c |
| 45 | - | cover reprint (on interior page) | 1 | pencils: Mike McKone; inks: Andy Lanning; colors: Jeromy Cox | Spider-Man [Peter Parker]; Jackpot [Alana Jobson] |
| 46 | Who Is Jackpot? | recap | 1 | letters: typeset | Jackpot [Alana Jobson] |
| 47 | A Tale of Two Jackpots | comic story | 37 | script: Marc Guggenheim; pencils: Mike McKone; inks: Andy Lanning; colors: Jeromy Cox, SotoColor; letters: VC, Cory Petit | Spider-Man [Peter Parker]; Jackpot [Alana Jobson]; Blindside; Walter Declun; Sara Ehret; Mr. Fantastic; Betty Brant; Commanda |
| 48 | The Amazing Return of John Romita Jr.! | text article | 8 | script: Dugan Trodglen; pencils: John Romita Jr. | |
| 49 | New Ways to Die: Inside the Spider-Office | text article | 6 | script: Dugan Trodglen; pencils: John Romita Jr. | |
| 50 | - | cover reprint (on interior page) | 1 | pencils: John Romita; inks: John Romita | Spider-Man [Peter Parker] |
| 51 | - | cover reprint (on interior page) | 0.5 | pencils: Alex Ross; inks: Alex Ross; colors: Alex Ross | Green Goblin [Norman Osborn] |
| 52 | - | cover reprint (on interior page) | 0.5 | pencils: Alex Ross; inks: Alex Ross; colors: Alex Ross | Green Goblin [Norman Osborn] |
| 53 | - | cover reprint (on interior page) | 1 | pencils: Adi Granov; inks: Adi Granov; colors: Adi Granov | Venom |
| 54 | - | cover reprint (on interior page) | 1 | pencils: Luke Ross; inks: Luke Ross; colors: Andres Mossa | Spider-Man [Peter Parker] |
| 55 | - | cover reprint (on interior page) | 1 | pencils: John Romita Jr.; inks: Klaus Janson; colors: Dean White | Anti-Venom [Eddie Brock] |
| 56 | - | cover reprint (on interior page) | 1 | pencils: David Finch; inks: Danny Miki; colors: Morry Hollowell | Bullseye |
| 57 | - | cover reprint (on interior page) | 1 | pencils: Kevin Maguire; inks: Kevin Maguire; colors: Dean White | Scorpion [Mac Gargan; Venom] |
| 58 | - | cover reprint (on interior page) | 1 | pencils: Marko Djurdjević; inks: Marko Djurdjević; colors: Marko Djurdjević | Spider-Man (zombie); Green Goblin (zombie) |
| 59 | - | cover reprint (on interior page) | 1 | pencils: Sal Buscema; inks: Sal Buscema; colors: Dean White | Spider-Man [Peter Parker] |