| 0 | - | cover | 1 | pencils: Ed McGuinness; inks: Mark Morales; colors: Jason Keith | Spider-Man [Peter Parker]; Deadpool [Wade Wilson]; Itsy Bitsy |
| 1 | - | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Mark Morales; colors: Jason Keith | Spider-Man [Peter Parker]; Deadpool [Wade Wilson]; Itsy Bitsy |
| 2 | Itsy Bitsy, Part 1 | comic story | 20 | script: Joe Kelly; pencils: Ed McGuinness; inks: Mark Morales; colors: Jason Keith; letters: Joe Sabino | Spider-Man [Peter Parker]; Deadpool [Wade Wilson]; Hateful Hexad [White Rabbit [Lorina Dodson]; Gibbon [Marty Blank]; Squid [Don Callahan]; Swarm [Fritz von Meyer]; Bearboarguy (introduction); Ox [Ronald Bloch]]; Itsy Bitsy [Susan Mary] |
| 3 | - | cover reprint (on interior page) | 1 | pencils: Julian Totino Tedesco; inks: Julian Totino Tedesco; colors: Julian Totino Tedesco | Spider-Man [Peter Parker]; Deadpool [Wade Wilson]; Spider-Man [Miles Morales]; Bamf; Patient Zero; Thor [Jane Foster]; Styx; Stone; Shiklah; Slapstick; Solo; Stingray [Walter Newell]; Foolkiller; Terror; Masacre; Mysterio [Quentin Beck] |
| 4 | - | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Mark Morales; colors: Jason Keith | Spider-Man [Peter Parker]; Deadpool [Wade Wilson]; Itsy Bitsy [Susan Mary]; Patient Zero |
| 5 | Itsy Bitsy, Part 2 | comic story | 20 | script: Joe Kelly; pencils: Ed McGuinness; inks: Mark Morales, Livesay, Jay Leisten, Ed McGuinness; colors: Jason Keith; letters: Joe Sabino | Spider-Man [Peter Parker]; Deadpool [Wade Wilson]; Itsy Bitsy [Susan Mary]; Patient Zero |
| 6 | - | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Mark Morales; colors: Jason Keith | Spider-Man [Peter Parker]; Deadpool [Wade Wilson] |
| 7 | Itsy Bitsy, Part 3 | comic story | 20 | script: Joe Kelly; pencils: Ed McGuinness; inks: Ed McGuinness, John Dell, Mark Morales; colors: Jason Keith; letters: Joe Sabino | Spider-Man [Peter Parker]; Deadpool [Wade Wilson]; Morgan Le Fay; Sl'Ur'Boroth |
| 8 | - | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Mark Morales; colors: Jason Keith | Spider-Man [Peter Parker]; Deadpool [Wade Wilson]; Nightcrawler [Kurt Wagner]; Bamfs |
| 9 | Itsy Bitsy, Part 4 | comic story | 20 | script: Joe Kelly; pencils: Ed McGuinness; inks: Mark Morales; colors: Jason Keith; letters: Joe Sabino | Spider-Man [Peter Parker]; Deadpool [Wade Wilson]; Nightcrawler [Kurt Wagner]; Bamfs; Shiklah; Weasel |
| 10 | - | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Mark Morales; colors: Jason Keith | Spider-Man [Peter Parker]; Deadpool [Wade Wilson]; Itsy Bitsy |
| 11 | Itsy Bitsy, Part 5 | comic story | 20 | script: Joe Kelly; pencils: Ed McGuinness; inks: Mark Morales, Walden Wong; colors: Jason Keith, Matt Yackey; letters: Joe Sabino | Spider-Man [Peter Parker]; Deadpool [Wade Wilson]; Itsy Bitsy; Anna Maria Marconi |
| 12 | - | cover reprint (on interior page) | 1 | pencils: Ed McGuinness; inks: Ed McGuinness; colors: Jason Keith | |
| 13 | Itsy Bitsy, Part 6 | comic story | 20 | script: Joe Kelly; pencils: Ed McGuinness; inks: Mark Morales; colors: Jason Keith; letters: Joe Sabino | Spider-Man [Peter Parker]; Deadpool [Wade Wilson]; Mephisto; Weasel; Itsy Bitsy |
| 14 | - | cover reprint (on interior page) | 1 | pencils: Whilce Portacio; inks: Whilce Portacio; colors: Chris Sotomayor | Spider-Man [Peter Parker]; Deadpool [Wade Wilson] |
| 15 | - | cover reprint (on interior page) | 1 | pencils: Todd Nauck; inks: Todd Nauck; colors: Rachelle Rosenberg | Deadpool [Wade Wilson]; Spider-Man [Peter Parker] |