| 0 | We Blow Up America's Biggest Jackass! | cover | 1 | pencils: Richard Williams; inks: Richard Williams | Johnny Knoxville; Alfred E. Neuman |
| 1 | A Mad Look at Jackass | comic story | 4 | script: Sergio Aragonés; pencils: Sergio Aragonés; inks: Sergio Aragonés | |
| 2 | Realistic Talking Toys! | photo story | 2 | script: Darren Johnson; pencils: Irving Schild; inks: Irving Schild | |
| 3 | You’ve Officially Become Your Mother/Father When… | comic story | 2 | script: Butch D'Ambrosio; pencils: Amanda Conner; inks: Amanda Conner | |
| 4 | Rap Music Predictions for the Coming Year | comic story | 3 | script: Arie Kaplan; pencils: Drew Friedman; inks: Drew Friedman | |
| 5 | The Lighter Side of... | comic story | 4 | script: Dave Berg; pencils: Dave Berg; inks: Dave Berg | Roger Kaputnik |
| 6 | One Fine Day Along the Yellow Brick Road | comic story | 1 | script: Michael Gallagher; pencils: James Warhola; inks: James Warhola | |
| 7 | Rejected Reality TV Shows | comic story | 2 | script: Greg Leitman; pencils: Hermann Mejía; inks: Hermann Mejía | |
| 8 | - | comic story | 2 | script: Peter Kuper; pencils: Peter Kuper; inks: Peter Kuper | |
| 9 | Monroe and… Jackass | comic story | 3 | script: Anthony Barbieri; pencils: Bill Wray; inks: Bill Wray | |
| 10 | Mad's Photo Personals Group | photo story | 3 | script: Jeff Kruse; pencils: Irving Schild; inks: Irving Schild | |
| 11 | Blind Man's Fluff | comic story | 2 | script: Duck Edwing; pencils: Duck Edwing; inks: Duck Edwing | |
| 12 | Questions You Never Want to Be Asked on a Summer Job Application | comic story | 3 | script: John Caldwell; pencils: John Caldwell; inks: John Caldwell; colors: Digital Chameleon | |
| 13 | Mad’s Complete Guide to Shipping Your Aging Relative Off to a Nursing Home | comic story | 4 | script: Mike Snider; pencils: Kevin Pope; inks: Kevin Pope | |
| 14 | AT&Fee Wireless Ad | text story | 1 | script: Dick DeBartolo | |
| 15 | Sluts in the City | comic story | 5 | script: Josh Gordon; pencils: Mort Drucker; inks: Mort Drucker | Sarah Jessica Parker [as Catty Broadshow]; Kim Cattrall [as Slamantha Johns]; Cynthia Nixon [as Marimba Hopps]; Kristin Davis [as Shallow Yorkie]; Chris Noth [as Mr. Biggie]; David Eigenberg [as Strive]; Kyle MacLachlan [as Tripe]; Brent; Scooter; Hagar the Horrible (cameo); Emilio; James Gandolfini |
| 16 | Mad's Celebrity Cause-Of-Death Betting Odds | comic story | 1 | script: Mike Snider; pencils: Hermann Mejía; inks: Hermann Mejía | Johnny Knoxville |
| 17 | What Televised Sports Disaster Horrified Millions of Viewers This Year? | illustration | 1 | script: Al Jaffee; pencils: Al Jaffee; inks: Al Jaffee | |